The sterile dry powder filling with rubber stoppering machine is a comprehensively designed compact sized model used for filling and stoppering of dry powder injectable into the vials. It comprises of a precision built frame that is coated with the stainless steel sheets with access doors. The model is designed sophisticatedly in accordance to the cGMP standards.
Process of operation
The aseptic dry powder filling machine comprises of sterilized powder that is stored in the powder hopper and supported by the mechanical agitators. Further it is the powder wheel in the machine that rotates at a speed below the powder hopper with no clearance. There is a doctor blade that thereby clears off the excess powder. Lastly the container is passed between two pressing rollers that accounts for tight fixing.
- The dry powder filling stoppering machine is a compact and cGMP model.
- It works on the principle of no-vial no-filling system.
- A multi-dosing system with a volumetric accuracy of nearly ± 1%.
- A safety clutch system for avoiding any kind of vial breakage.
- The contact parts are exclusively configured with stainless steel that is useful for autoclaving and sterilization.
- Comprises of a digital counter that is used for counting production output.
- Acrylic based cabinet with imported aluminum structure for machines, unscrambled and scrambler.
- Pure air filters available for air and vacuum.
- Pre and post gassing unit available for nitrogen and carbon di oxide flushing.
- A.C. Frequency drives available
- No stopper system in chute and machine stop system.
- Assemblies placed in a position to clean and maintain.
- Vibratory bowl available for running machine with total claimed speed.
Here are the technical specifications of the product:
|Production Rate||30 to 120 Vials/Minute||60 to 240 Vials/Minute|
|Container Diameter:||25mm to 38mm||25mm to 38mm|
|Container Height:||36mm to 75mm||36mm to 75mm|
|Rubber Stopper:||20mm, 28mm & 30mm Butyl||20mm, 28mm & 30mm Butyl|
|Fill Capacity||50 mg. to 1.5 gms with the help of change parts. Up to 6 gms filling by multiple dosing.||50 mg. to 1.5 gms with the help of change parts. Up to 6 gms filling by multiple dosing.|
|Accuracy:||± 1% depending upon consistency and uniformity of bulk density of Injectable Powder under controlled level of humidity (Below 28% Rh)||± 1% depending upon consistency and uniformity of bulk density of Injectable Powder under controlled level of humidity (Below 28% Rh)|
|Optional Accessories:||Pure Air Filter, Vacuum Pump||Pure Air Filter, Vacuum Pump|
|-||Oil Free Air Compressor||Oil Free Air Compressor|
|-||Online Pre-Media Filling Arrangement||Online Pre-Media Filling Arrangement|
|-||Programmable Logic Control (System) with MMI||Programmable Logic Control (System) with MMI|
|-||Aluminum Profile Cabinet covering full machine||Aluminum Profile Cabinet covering full machine|
|Compressed Air:||Max. 2 Kg./Cm² Oil Free||Max. 2 Kg./Cm² Oil Free|
|Vacuum:||25 Hg. @ 300 LPM Displacement||25 Hg. @ 300 LPM Displacement|
|Relational Humidity:||Below 28%||Below 28%|
|Overall Dimension:||2100mm (L) X 842mm (W) X 1700mm (H)||2300mm (L) X 842mm (W) X 1700mm (H)|